{"id":2244,"date":"2026-01-28T14:09:24","date_gmt":"2026-01-28T13:09:24","guid":{"rendered":"https:\/\/studienportal-eierstockkrebs.de\/nis-niraparib-noggo-ov45-carolin\/"},"modified":"2026-02-13T13:23:26","modified_gmt":"2026-02-13T12:23:26","slug":"nis-niraparib-noggo-ov45-carolin","status":"publish","type":"post","link":"https:\/\/studienportal-eierstockkrebs.de\/vi\/nis-niraparib-noggo-ov45-carolin\/","title":{"rendered":"NIS Niraparib \u2013 NOGGO-ov45 \u2013 CAROLIN"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"2244\" class=\"elementor elementor-2244 elementor-842\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4b75352e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4b75352e\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-cf9f728\" data-id=\"cf9f728\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-12254b72 elementor-widget elementor-widget-heading\" data-id=\"12254b72\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">  NIS Niraparib \u2013 NOGGO-ov45 \u2013 CAROLIN<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-52911afa elementor-widget elementor-widget-text-editor\" data-id=\"52911afa\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 class=\"blue\"><strong>D\u00e0nh cho b\u1ec7nh nh\u00e2n ung th\u01b0 bu\u1ed3ng tr\u1ee9ng nh\u1ea1y c\u1ea3m v\u1edbi platin kh\u00f4ng c\u00f3 ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh v\u1edbi niraparib.<\/strong><\/h2>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t<div class=\"elementor-element elementor-element-a8ec989 e-flex e-con-boxed e-con e-parent\" data-id=\"a8ec989\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-27c5762 elementor-widget elementor-widget-image\" data-id=\"27c5762\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"http:\/\/studienportal-eierstockkrebs.de\/wp-content\/uploads\/Studie_NIS-Carolin_01-1.jpg\" data-elementor-open-lightbox=\"yes\" data-e-action-hash=\"#elementor-action%3Aaction%3Dlightbox%26settings%3DeyJpZCI6ODQ0LCJ1cmwiOmZhbHNlfQ%3D%3D\">\n\t\t\t\t\t\t\t<img decoding=\"async\" src=\"http:\/\/studienportal-eierstockkrebs.de\/wp-content\/uploads\/Studie_NIS-Carolin_01-1.jpg\" title=\"\" alt=\"\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-69fa2007 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"69fa2007\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-48cd7a65\" data-id=\"48cd7a65\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-54f48f09 elementor-widget elementor-widget-text-editor\" data-id=\"54f48f09\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Nghi\u00ean c\u1ee9u quan s\u00e1t kh\u00f4ng can thi\u1ec7p n\u00e0y nh\u1eb1m m\u1ee5c \u0111\u00edch \u0111i\u1ec1u tra li\u1ec7u ph\u00e1p niraparib d\u00e0i h\u1ea1n \u1edf b\u1ec7nh nh\u00e2n ung th\u01b0 bu\u1ed3ng tr\u1ee9ng nh\u1ea1y c\u1ea3m v\u1edbi platin m\u1edbi \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n ho\u1eb7c t\u00e1i ph\u00e1t, v\u00e0 x\u00e1c \u0111\u1ecbnh c\u00e1c y\u1ebfu t\u1ed1 li\u00ean quan \u0111\u1ebfn s\u1ef1 s\u1ed1ng s\u00f3t l\u00e2u d\u00e0i. Niraparib l\u00e0 m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf PARP gi\u00fap k\u00e9o d\u00e0i t\u00e1c d\u1ee5ng c\u1ee7a h\u00f3a tr\u1ecb sau khi ho\u00e0n t\u1ea5t b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf c\u00e1c c\u01a1 ch\u1ebf s\u1eeda ch\u1eefa trong c\u00e1c t\u1ebf b\u00e0o ung th\u01b0 b\u1ecb t\u1ed5n th\u01b0\u01a1ng do h\u00f3a tr\u1ecb. C\u00e1c t\u1ebf b\u00e0o b\u1ecb t\u1ed5n th\u01b0\u01a1ng sau \u0111\u00f3 kh\u00f4ng th\u1ec3 t\u00e1i t\u1ea1o v\u00e0 ch\u1ebft \u0111i.  <\/strong><\/p><p><strong>M\u1ee5c \u0111\u00edch c\u1ee7a nghi\u00ean c\u1ee9u n\u00e0y l\u00e0 g\u00ec?<\/strong><\/p><p>M\u1ee5c ti\u00eau l\u00e0 x\u00e1c \u0111\u1ecbnh nh\u1eefng \u0111\u1eb7c \u0111i\u1ec3m \u0111i\u1ec3n h\u00ecnh n\u00e0o li\u00ean quan \u0111\u1ebfn b\u1ec7nh, ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb v\u00e0 b\u1ec7nh nh\u00e2n c\u00f3 li\u00ean quan \u0111\u1ebfn kh\u1ea3 n\u0103ng s\u1ed1ng s\u00f3t l\u00e2u d\u00e0i. Nghi\u00ean c\u1ee9u c\u0169ng s\u1ebd \u0111i\u1ec1u tra nh\u1eefng y\u1ebfu t\u1ed1 c\u1ee5 th\u1ec3 n\u00e0o c\u1ee7a vi\u1ec7c s\u1eed d\u1ee5ng niraparib (li\u1ec1u l\u01b0\u1ee3ng, t\u00e1c d\u1ee5ng ph\u1ee5, th\u1eddi gian \u0111i\u1ec1u tr\u1ecb, ch\u1ea5t l\u01b0\u1ee3ng cu\u1ed9c s\u1ed1ng trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb) c\u00f3 t\u01b0\u01a1ng quan v\u1edbi kh\u1ea3 n\u0103ng s\u1ed1ng s\u00f3t l\u00e2u d\u00e0i. <\/p><p><strong>Quy tr\u00ecnh nghi\u00ean c\u1ee9u nh\u01b0 th\u1ebf n\u00e0o?<\/strong><\/p><p>\u0110\u00e2y l\u00e0 m\u1ed9t <strong>nghi\u00ean c\u1ee9u quan s\u00e1t<\/strong> , trong \u0111\u00f3 quy\u1ebft \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb b\u1eb1ng niraparib \u0111\u01b0\u1ee3c \u0111\u01b0a ra b\u1edfi b\u00e1c s\u0129 v\u00e0 b\u1ec7nh nh\u00e2n tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u nghi\u00ean c\u1ee9u, v\u00e0 li\u1ec7u ph\u00e1p \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n theo ph\u00e1c \u0111\u1ed3 chu\u1ea9n. D\u1eef li\u1ec7u b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c thu th\u1eadp v\u00e0o \u0111\u1ea7u nghi\u00ean c\u1ee9u v\u00e0 c\u1ee9 s\u00e1u th\u00e1ng m\u1ed9t l\u1ea7n sau \u0111\u00f3, cho \u0111\u1ebfn t\u00e1m n\u0103m sau khi tham gia nghi\u00ean c\u1ee9u. <\/p><p><strong>C\u00f3 r\u1ee7i ro n\u00e0o kh\u00f4ng?<\/strong><\/p><p>\u0110\u00e2y l\u00e0 m\u1ed9t nghi\u00ean c\u1ee9u ho\u00e0n to\u00e0n mang t\u00ednh quan s\u00e1t, ngh\u0129a l\u00e0 b\u1ec7nh nh\u00e2n kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng th\u00eam b\u1ea5t k\u1ef3 lo\u1ea1i thu\u1ed1c ho\u1eb7c ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb n\u00e0o kh\u00e1c. Do \u0111\u00f3, nh\u1eefng ng\u01b0\u1eddi tham gia nghi\u00ean c\u1ee9u kh\u00f4ng ph\u1ea3i ch\u1ecbu b\u1ea5t k\u1ef3 r\u1ee7i ro ho\u1eb7c t\u00e1c d\u1ee5ng ph\u1ee5 n\u00e0o kh\u00e1c. Tuy nhi\u00ean, vi\u1ec7c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng niraparib, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong tr\u01b0\u1eddng h\u1ee3p t\u00e1i ph\u00e1t \u1edf b\u1ec7nh nh\u00e2n ung th\u01b0 bu\u1ed3ng tr\u1ee9ng sau h\u00f3a tr\u1ecb, c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nh\u01b0 thi\u1ebfu ti\u1ec3u c\u1ea7u, thi\u1ebfu m\u1ed9t s\u1ed1 lo\u1ea1i b\u1ea1ch c\u1ea7u (b\u1ea1ch c\u1ea7u trung t\u00ednh), thi\u1ebfu m\u00e1u, huy\u1ebft \u00e1p cao ho\u1eb7c h\u1ed9i ch\u1ee9ng m\u1ec7t m\u1ecfi.  <\/p><p class=\"blue\"><strong>Y\u00eau c\u1ea7u tham gia<\/strong><\/p><p>Nghi\u00ean c\u1ee9u n\u00e0y d\u00e0nh cho ph\u1ee5 n\u1eef t\u1eeb 18 tu\u1ed5i tr\u1edf l\u00ean m\u1eafc ung th\u01b0 bu\u1ed3ng tr\u1ee9ng, \u1ed1ng d\u1eabn tr\u1ee9ng ho\u1eb7c ph\u00fac m\u1ea1c, m\u1edbi \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n ho\u1eb7c t\u00e1i ph\u00e1t (\u0111\u01b0\u1ee3c x\u00e1c nh\u1eadn b\u1eb1ng k\u1ebft qu\u1ea3 m\u00f4 h\u1ecdc) v\u00e0 \u0111\u00e3 \u0111\u00e1p \u1ee9ng \u0111i\u1ec1u tr\u1ecb h\u00f3a tr\u1ecb. B\u1ec7nh nh\u00e2n ph\u1ea3i ph\u00f9 h\u1ee3p v\u1edbi li\u1ec7u ph\u00e1p duy tr\u00ec b\u1eb1ng niraparib, ngh\u0129a l\u00e0 kh\u00f4ng c\u00f3 ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh v\u00e0 c\u00f3 kh\u1ea3 n\u0103ng t\u1ef1 u\u1ed1ng thu\u1ed1c m\u1ed9t c\u00e1ch \u0111\u1ed9c l\u1eadp v\u00e0 \u0111\u00e1ng tin c\u1eady. B\u1ec7nh nh\u00e2n qu\u00e1 m\u1eabn v\u1edbi thu\u1ed1c, \u0111ang mang thai ho\u1eb7c \u0111ang cho con b\u00fa kh\u00f4ng \u0111\u1ee7 \u0111i\u1ec1u ki\u1ec7n tham gia.  <\/p><p><strong>T\u00f4i c\u00f3 th\u1ec3 tham gia nghi\u00ean c\u1ee9u \u1edf \u0111\u00e2u?<\/strong><\/p><p class=\"blue\"><strong>Nghi\u00ean c\u1ee9u n\u00e0y \u0111\u01b0\u1ee3c t\u00e0i tr\u1ee3 b\u1edfi:<\/strong><\/p><p>C\u00f4ng ty d\u01b0\u1ee3c ph\u1ea9m nghi\u00ean c\u1ee9u <strong>GLAXOSMITHKLINE<\/strong> l\u00e0 \u0111\u1ed1i t\u00e1c trong nghi\u00ean c\u1ee9u n\u00e0y.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>NIS Niraparib \u2013 NOGGO-ov45 \u2013 CAROLIN D\u00e0nh cho b\u1ec7nh nh\u00e2n ung th\u01b0 bu\u1ed3ng tr\u1ee9ng nh\u1ea1y c\u1ea3m v\u1edbi platin kh\u00f4ng c\u00f3 ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh v\u1edbi niraparib. Nghi\u00ean c\u1ee9u quan s\u00e1t kh\u00f4ng can thi\u1ec7p n\u00e0y nh\u1eb1m m\u1ee5c \u0111\u00edch \u0111i\u1ec1u tra li\u1ec7u ph\u00e1p niraparib d\u00e0i h\u1ea1n \u1edf b\u1ec7nh nh\u00e2n ung th\u01b0 bu\u1ed3ng tr\u1ee9ng nh\u1ea1y c\u1ea3m v\u1edbi platin m\u1edbi [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[67,68],"tags":[],"class_list":["post-2244","post","type-post","status-publish","format-standard","hentry","category-nghien-cuu","category-tai-phat"],"acf":[],"_links":{"self":[{"href":"https:\/\/studienportal-eierstockkrebs.de\/vi\/wp-json\/wp\/v2\/posts\/2244","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/studienportal-eierstockkrebs.de\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/studienportal-eierstockkrebs.de\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/studienportal-eierstockkrebs.de\/vi\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/studienportal-eierstockkrebs.de\/vi\/wp-json\/wp\/v2\/comments?post=2244"}],"version-history":[{"count":1,"href":"https:\/\/studienportal-eierstockkrebs.de\/vi\/wp-json\/wp\/v2\/posts\/2244\/revisions"}],"predecessor-version":[{"id":2245,"href":"https:\/\/studienportal-eierstockkrebs.de\/vi\/wp-json\/wp\/v2\/posts\/2244\/revisions\/2245"}],"wp:attachment":[{"href":"https:\/\/studienportal-eierstockkrebs.de\/vi\/wp-json\/wp\/v2\/media?parent=2244"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/studienportal-eierstockkrebs.de\/vi\/wp-json\/wp\/v2\/categories?post=2244"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/studienportal-eierstockkrebs.de\/vi\/wp-json\/wp\/v2\/tags?post=2244"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}